tag:blogger.com,1999:blog-1887866819730206489.post1813632378192190467..comments2023-09-21T10:01:01.839-06:00Comments on Fantastic Voyage: A journey through my DNA and Personal Genomics: What is this all about?Grant M. Woodhttp://www.blogger.com/profile/18185402177712853914noreply@blogger.comBlogger13125tag:blogger.com,1999:blog-1887866819730206489.post-28770226804118261902023-05-15T22:11:04.627-06:002023-05-15T22:11:04.627-06:00bape outlet
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Alot of blogs I see these d...Very interesting blog. Alot of blogs I see these days don't really provide anything that I'm interested in, but I'm most definately interested in this one. Just thought that I would post and let you know. <a href="https://dnatestnutrition.picturepush.com/profile" rel="nofollow">DNA test nutrition</a>seo pormotionhttps://www.blogger.com/profile/00987115700887642371noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-22068362027185785562019-06-24T07:59:29.514-06:002019-06-24T07:59:29.514-06:00I’m from USA am here to give my testimony about Dr...I’m from USA am here to give my testimony about Dr Mack who helped me cure my HERPES (HSV), i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS), i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. Three months ago a friend suggested that I try herbal medicine; from a very powerful herbal doctor called (Dr.Robinson) I looked up his blog on the internet site and indeed he have had immense success with his product. There were lot of persons posting their testimony about how he cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, my HERPES result just came out negative. (Robinson.buckler (@ yahoo). com 🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂🙂<br /><br />Celina Jeffhttps://www.blogger.com/profile/16326665565025421362noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-42672232602391732902018-12-27T02:16:54.670-07:002018-12-27T02:16:54.670-07:00Genetic testing suggests the possibility of an app...Genetic testing suggests the possibility of an approach to health care in which risk reduction and treatment are individually tailored.DNA testing for health reasonshttps://originalgene.com/how-it-worksnoreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-9197898691199243772009-06-23T23:53:13.054-06:002009-06-23T23:53:13.054-06:00I'm late getting in on this particular convers...I'm late getting in on this particular conversation, but upon reading Marc's comments about his initial response as a "typical doctor" I had to smile. It's refreshing to see that this blog appears to be willing to take a deeper look into our own past patterns, many of which may have unwittingly been keeping us stuck in place.<br /><br />I was also happy to see the British response to what they viewed as a paternalistic regression. As Marc said so aptly, it is certainly the time and age where patients are in need of and hungering (if not demanding) that they be treated like responsible adults that have the right to be privy to their own information and allowed to participate more fully in the decisions and path of their healthcare.<br /><br />Will this require the medical establishment to become better educators and coaches in bringing some patients to a more complete understanding of the ramifications of the information they may access? Yes, but this is part of the empowerment process. For empowerment not only requires that we give access, but that we provide the opportunity for patients to more thoroughly educate themselves so they might participate more fully and capably in making the decisions about their lives and their health.<br /><br />It's wonderful to see this discussion taking form and the mechanisms being contemplated and put in place that enable the beginning steps in this process to take place.<br /><br />Kudos!CLHnoreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-82640413004649706182009-06-08T22:49:06.184-06:002009-06-08T22:49:06.184-06:00Marc,
I enjoyed your response. Several questions ...Marc,<br /><br />I enjoyed your response. Several questions come to mind, not the least being the potential effect of commercial imperatives on the integrity of legitimately complex information, but it seems only fair to let the process unfold without prejudging those things. <br /><br />One thought, though, may perhaps address our continuing question of authority in the context of direct-to-consumer genetic testing. Your comment about the fact that there is still some distance to go before it can be determined what material is truly useful in this field was refreshingly honest and seems really sensible in light of the speed with which it’s all developing. The distinction you draw between the field’s good understanding of single gene diseases as opposed to the much fuzzier area of genetic involvement in common diseases made me think a lot. It seems to me that there is a rather large difference between simple data (quanta of meaning that represent the relationship of the observed characteristics of some physical entity to an assigned value scale) and information (data integrated into contextual frames that can be deployed to effect change in the equilibrium of a given system). <br /><br />In other words, there seems to be an awful lot of territory between having the numbers and knowing what the numbers cook down to in the life of the patient receiving them. How that territory gets navigated, and by whom, seems to me to form the central question around the potential utility of direct-to-consumer testing. I’m hoping that your dialog with Grant will open some of those questions up. As an interested (VERY) non-expert, I’m grateful for the opportunity to eavesdrop on the project and learn from both of you. <br /><br />And BTW, with respect to your comments about the idea of qi and its often tortured interactions with mainstream medicine, I think they probably have more commonalities with the current discussion than might be immediately apparent, but that’s another discussion for another blog.bkohttps://www.blogger.com/profile/12652614289943658318noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-37371852576557883942009-06-04T22:18:53.494-06:002009-06-04T22:18:53.494-06:00Grant - Good for you! I have also been thinking a...Grant - Good for you! I have also been thinking about doing one of those tests. My reasons are similar to yours, but with some added twists. I was an orphan. I kind of know what my lineage is, at least as per the family bibles handed down over the years mixed with some on line public genealogy records, and who knows how accurate those are? However, both of my lines go WAY back to the very very early days of the colonization of America. We go back long before the Revolutionary war. Also, Dad's side fought for Abraham Lincoln while Mom's side was from the deep south, but both sides go back to the earliest settlers. Given the human population inhabiting the east coast in those early days, it's hard for me to believe that my heritage is 100% Northern European, although I am clearly of Viking decent, as anyone who knows me can attest to. OK, so at least if the records are right, I am a descendent of Chaucer - Of Englande to Canterbury they went Chaucer. Which is cool, but I'd be really tickled to see some native American blood or some African American blood floating around in there. I think it would add to my all-American mixed pot religious renegade family story. <br /><br />I would like to know how scientifically honest the tests and test results are, both on the genetic SNP interpretation as well as on their ability to geographically locate one's ancestors. I have heard that if you send in samples to several different DTC genetic tests, you'll get several different answers. And of course, I already know that the SNPs they report are usually so minor that they are generally not considered disease indicators even if they are in important genes.<br /><br />Finally, as a licensing professional, I'm curious to see how blatantly they are infringing intellectual property. They are, believe me. However, as I said earlier, they are generally reporting minor mutations so no one cares. If they were reporting the important mutations, companies like Myriad or Clinical Data would be on them like an antibody to an antigen. It's sad to think that people believe they are getting BRCA1 and BRCA2 testing when they order these. <br /><br />All in all, I hope you are willing to share your opinions about some of these important issues. Thanks for posting, and thanks for inviting comments!Sheryl Hohlehttp://www.linkedin.com/in/shohlenoreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-50392948126697418542009-06-03T22:09:15.918-06:002009-06-03T22:09:15.918-06:00bko,
Really interesting post. In many ways as I ...bko,<br /><br />Really interesting post. In many ways as I look at the realm of genetics and genetic information I increasingly conclude that the "community of experts" has yet to emerge. While I believe that geneticists and genetic counselors can fairly claim expertise in the area of rare single gene genetic disease, it is not so clear in the area of genetic risk for common disease. As you note, we really don't understand what is useful. For the most part we are currently talking about changing health behaviors. This is incredibly hard to do, yet many believe that genetic information will somehow provide the motivation to change that the biomarkers Steve references have not. That's a key area to study. As we walk through Grant's results we'll hopefully be able to put this into some context (and you can decide about whether any of us have any claim to authority).<br />I also wanted to share an anecdote to address your epistemological example. I was at a talk where the speaker (an allopathic physician) asked the audience how many believe that acupuncture worked? Most of us raised our hands. He then asked who believed in qi? No one raised their hand. He then stated that if you don't believe in qi you can't believe acupuncture works. How arrogant yet emblematic of many in the Western sciences. We discount empirical observation if we can't understand (or choose to dismiss) the mechanism. A scientist is obligated to assess the validity of the empirical observation, but if it exists then one must use the observation as a starting point to try and understand the mechanism. Only then can we begin to learn.Marc S. Williams, MDhttp://drmarc.gather.comnoreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-36213633062432106162009-06-03T10:38:39.244-06:002009-06-03T10:38:39.244-06:00Steve,
Because of the fact that my father had a t...Steve,<br /><br />Because of the fact that my father had a triple bypass done, I do know my HDL (not great), CardioCRP (good), and blood pressure (very good). I have learned that these readings, which can change for better or worse over time - unlike my DNA - are more important than the less than one-tenth of one percent of my genome that I currently know. The point you make is key, that the genetic service I did does not replace the standard clinical tests. But, they do not claim to anyway. We plan to address this issue in more depth with future posts.Grant M. Woodhttps://www.blogger.com/profile/18185402177712853914noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-12057437355216756732009-06-03T07:46:34.469-06:002009-06-03T07:46:34.469-06:00Congratulations on your new blog. Glad you are rec...Congratulations on your new blog. Glad you are recruiting genetics professionals to serve as your "Sherpas".....Wise decision. I look forward to your blog and will add it to my roll.<br /><br />BTW Grant, do you know your HDL, CardioCRP, Blood Pressure and Family History of heart disease? These could be way more valuabe to you than the less than 1% of your genome that you just peeked at.......<br /><br />All the best,<br />-Steve<br />www.thegenesherpa.blogspot.comSteve Murphy MDhttps://www.blogger.com/profile/11774190000307343476noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-23814287814541207472009-06-01T14:04:19.961-06:002009-06-01T14:04:19.961-06:00Two general questions (at least!) circle around th...Two general questions (at least!) circle around this whole area as they do around any activity that involves consulting an "expert", whether it's a person or a system. <br /><br />1- How usable is the information for the person seeking it? <br /><br />2- How much of the information/interpretation that's being given is limited to the subjective take of the "expert" and how much is coming from consensus data established by the community of experts in that field?<br /><br />Also, as Marc used the herbal example, that issue can be used to ask a question about whether the "consensus" data itself is flawed or biased in relationship to other communities of experts, e.g. the prevailing views of Western pharmaceutically-based providers using biochemistry and western physiology as the entry language for studying herbal medicine vs. the community of professional Chinese medical herbal practitioners who have been using the technology for millenia, but whose expertise is derived from an entirely different epistemological base and is expressed in an entirely different technical language. <br /><br />At the end of it, it comes down to who actually has the authority claim for genetics, and in a field so newly emergent, how far do those authority claims legitimately extend? It would seem to me that answering that question would be the only way to ultimately figure out if a mail-in direct-to-consumer test panel would be of potential benefit or of harm. That would be the only way to determine what parts of this legitimately complex field are capable of generating data that are directly usable by consumers and which ones require specialist knowledge in order to have any on-the-ground-value.<br /><br />Cool blog. I'll enjoy watching it progress.bkohttps://www.blogger.com/profile/12652614289943658318noreply@blogger.comtag:blogger.com,1999:blog-1887866819730206489.post-17058524584614940962009-06-01T12:58:46.924-06:002009-06-01T12:58:46.924-06:00Thanks for sharing your combined experience, I'll ...Thanks for sharing your combined experience, I'll look forward to your observations as this moves forward.Mark Hoffmanhttps://www.blogger.com/profile/15581934580987862889noreply@blogger.com